BIO-32546

CAS No. 1548743-66-3

BIO-32546( —— )

Catalog No. M32810 CAS No. 1548743-66-3

BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
5MG 550 In Stock
10MG 905 In Stock
25MG 1891 In Stock
50MG 2967 In Stock
100MG 4771 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BIO-32546
  • Note
    Research use only, not for human use.
  • Brief Description
    BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.
  • Description
    BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator (IC50: 1 nM), extracted from the patent US20170158687A1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1548743-66-3
  • Formula Weight
    543.54
  • Molecular Formula
    C28H31F6NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (183.98 mM; Ultrasonic )
  • SMILES
    C(F)(F)(F)C=1C2=C(C=CC1O[C@@H]3CC[C@H](C(F)(F)F)CC3)C=CC([C@H](C)N4C5(CC(C(O)=O)CC4(CC5)[H])[H])=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kevin M. Guckian, et al. Atx modulating agents. Patent. US20170158687A1.
molnova catalog
related products
  • BI 1015550

    Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM. BI 1015550 has potential applications in inflammation, allergic diseases, pulmonary fibrosis and chronic obstructive pulmonary disease (COPD) with a good safety profile.

  • BI-409306

    BI-409306 is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.

  • SCH-00013

    A novel cardiotonic agent that acts as a calcium sensitizer with no chronotropic activity in mammalian cardiac muscle.