AVE5688( —— )

Catalog No. M32794 CAS No. 613260-13-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

AVE5688
Note

Research use only, not for human use.
Brief Description

AVE5688, an inhibitor of glycogen phosphorylase (GP), has IC50 values of 430 nM and 915 nM, and Kd values of 170 nM and 530 nM for rmGPb and rmGPa, respectively.
Description

AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively); AVE5688 can be used for the research of type 2 diabetes.
In Vitro

AVE5688 is an inhibitor of glycogen phosphorylase (GP), with IC50s of 430 nM and 915 nM and Kds of 170 nM and 530 nM for rabbit muscle glycogen phosphorylase (rmGPb and rmGPa, respectively).
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Phosphorylase
Research Area

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Indication

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1. Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47(16):4683-91.?

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