Adenosine 5-diphosphoribose sodium( —— )

Catalog No. M32769 CAS No. 68414-18-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Adenosine 5-diphosphoribose sodium
Note

Research use only, not for human use.
Brief Description

Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) is a metabolite of nicotinamide adenine nucleotide (NAD+), which is widely present in organisms.
Description

Adenosine 5′-diphosphoribose sodium (ADP ribose sodium) is a nicotinamide adenine nucleotide (NAD+) metabolite. Adenosine 5′-diphosphoribose sodium is the most potent and primary intracellular Ca2+-permeable cation TRPM2 channel activator. Adenosine 5′-diphosphoribose sodium also can enhance autophagy.
In Vitro

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In Vivo

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Synonyms

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Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

TRP/TRPV Channel | Autophagy | Endogenous Metabolite
Research Area

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Indication

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CAS Number

68414-18-6
Formula Weight

581.3
Molecular Formula

C15H22N5NaO14P2
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 125 mg/mL (215.04 mM; Ultrasonic) DMSO : 25 mg/mL (43.01 mM; Ultrasonic (<80°C)
SMILES

O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OC[C@@H](O)[C@@H](O)[C@@H](O)C=O)([O-])=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[Na+]
Chemical Name

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1. Zhang DX, et al. The potential regulatory roles of NAD(+) and its metabolism in autophagy. Metabolism. 2016 Apr;65(4):454-62.?

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