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7-BIA
CAS No. 1313403-49-4
7-BIA( —— )
Catalog No. M32759 CAS No. 1313403-49-4
7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 377 | In Stock |
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| 5MG | 353 | In Stock |
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| 10MG | 613 | In Stock |
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| 25MG | 1131 | In Stock |
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| 50MG | 1748 | In Stock |
|
| 100MG | 2771 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name7-BIA
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NoteResearch use only, not for human use.
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Brief Description7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.
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Description7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with an IC50 of ~1-3 μM.
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In Vitro——
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In VivoAnimal Model:WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions) Dosage:10 mg/kg, 20 mg/kg Administration:Given i.p.; only once Result:Reduced cocaine self-administration in highly experienced WT mice.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorPhosphatase
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Research Area——
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Indication——
Chemical Information
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CAS Number1313403-49-4
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Formula Weight294.3
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Molecular FormulaC15H18O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (424.74 mM; Ultrasonic ) Ethanol : 50 mg/mL (169.89 mM; Ultrasonic)
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SMILESCCCCOc1cc2C(=O)OC(O)Cc2c(C=O)c1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Uhl GR, et al. Cocaine reward is reduced by decreased expression of receptor-type protein tyrosinephosphatase D (PTPRD) and by a novel PTPRD antagonist. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):11597-11602.?
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