PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively suppressing PCSK9 expression.

Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals. Schisanhenol has anti-apoptosis effect on BACSs, may be related to its inhibition of ROS generation.

CDDO-3P-Im, an analog of CDDO-Imidazolide, has a chemopreventive effect. It can reduce the size and severity of the lung tumors in the mouse lung cancer model.