Brandioside shows strong antioxidant, and neuroprotective effects, it significantly attenuates glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 microM; it exhibits significant inhibition of advanced glycation end product formation with the IC50 value of 4.6-25.7 μM.

5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one is a natural product of Agave, Amaryllidaceae. 5-Hydroxy-3-(4-hydroxybenzyl)-7-methoxychroman-4-one can be used as a reference standard.

PF-06952229 is an selective and orally active inhibitor of TGFbR1.