1R,3S-RSL 3 is a harmala alkaloid.

Trimethylamine N-oxide dihydrate a product of the oxidation of trimethylamine is considered as a protein stabilizer that may serve to counteract urea the major osmolyte of sharks skates and rays.

Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus.