Leucosceptoside A
CAS No. 83529-62-8
Leucosceptoside A( —— )
Catalog No. M31560 CAS No. 83529-62-8
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 519 | In Stock |
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| 5MG | 392 | In Stock |
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| 10MG | 560 | In Stock |
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| 25MG | 892 | In Stock |
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| 50MG | 1172 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLeucosceptoside A
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NoteResearch use only, not for human use.
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Brief DescriptionLeucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase.
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DescriptionLeucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows angiotensin converting enzyme (ACE) inhibitory effect in a dose-dependent manner of which IC(50) value of 423+/-18.8 microg/ml.
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In VitroLeucosceptoside A shows weak angiotensin converting enzyme (ACE) inhibitory effect.Leucosceptoside A (4-16 μM) significantly reduces 1-methyl-4-phenylpyridinium ion (MPP+)-induced death of mesencephalic neurons.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number83529-62-8
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Formula Weight638.61
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Molecular FormulaC30H38O15
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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[Leu144,Arg147]-Myel...
[Leu144,Arg147]-PLP (139-151) is a mutant peptide fragment of myelin proteolipid protein (PLP), with the tryptophan and histidine at positions 144 and 147 respectively replaced by leucine and arginine. [Leu144,Arg147]-PLP (139-151) also serves as a T cell receptor (TCR) antagonist for encephalitogenic Th1 clones, blocking their activation in vitro. Furthermore, [Leu144,Arg147]-PLP (139-151) can inhibit the development of experimental autoimmune encephalomyelitis (EAE).
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