Coelonin( —— )

Catalog No. M31311 CAS No. 82344-82-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Coelonin
Note

Research use only, not for human use.
Brief Description

Coelonin shows moderate cytotoxic activity against HepG2 cells.
Description

Coelonin shows moderate cytotoxic activity against HepG2 cells.
In Vitro

Western Blot Analysis Cell Line:RAW264.7 cells Concentration:0, 1, 2.5, and 5 μg/mL Incubation Time:1.5 h Result:Dose dependently reduced the increase of p65 accumulation in the nucleus induced by LPS. Dose dependently reversed LPS-induced iNOS and COX2 expression. LPS (200 ng/mL) significantly increased the phosphorylation of PTEN, AKT and inhibitor of NF-κB (IκBa), which was dose-dependently reduced by coelonin pre-treatment.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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