Cannabisin F

Research use only, not for human use.

Melongenamides B-D and Cannabisin F have anti-inflammatory activity, they exhibit inhibitions of nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophages with IC50 values ranging from 16.2 to 58.5 uM.

Melongenamides B-D and Cannabisin F have anti-inflammatory activity, they exhibit inhibitions of nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophages with IC50 values ranging from 16.2 to 58.5 uM.

Cannabisin F (0~15 μM; 1 hour; BV2 microglia cells) inhibits the phosphorylation of IκBα, p65, but enhances the expression of Nrf2 and HO-1.Cannabisin F (0~15 μM; 24 hours; BV2 microglia cells) has no significant effect on cell survival, inhibits IL-6 and TNF-α production and their mRNA expression, inhibits the production of ROS and increases the expression of SIRT1. Cell Viability Assay Cell Line:BV2 microglia cells Concentration:0~15 μM Incubation Time:24 hours Result:Had no significant effect on cell survival.Western Blot Analysis Cell Line:BV2 microglia cells Concentration:0~15 μM Incubation Time:1 hour Result:Inhibited the phosphorylation of IκBα, p65, but enhanced the expression of Nrf2 and HO-1.

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Others

Other Targets

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163136-19-4

624.69

C36H36N2O8

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years