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Magainin 1
CAS No. 108433-99-4
Magainin 1( —— )
Catalog No. M30461 CAS No. 108433-99-4
Magainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 425 | Get Quote |
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| 10MG | 721 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMagainin 1
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NoteResearch use only, not for human use.
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Brief DescriptionMagainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis.
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DescriptionMagainin 1 is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. (In Vitro):Magainin 1 interacts with acidic lipids through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8×105 M-1 and a binding-site number of 0.10 per lipid molecule.
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In VitroMagainin 1 interacts with acidic lipids through electrostatic interactions followed by hydrophobic interactions to form an amphiphilic helix, inducing the leakage. Magainin 1 induces the leakage of calcein specifically out of negatively-charged vesicles. The peptide binds to bovine brain phosphatidylserine sonicated vesicles according to the Langmuir isotherm with a binding constant of 3.8×105 M-1 and a binding-site number of 0.10 per lipid molecule.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number108433-99-4
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Formula Weight2409.85
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Molecular FormulaC112H177N29O28S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 100 mg/mL (41.50 mM)
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SMILES——
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Chemical NameSequence:Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Duclohier H, et al. Antimicrobial peptide magainin I from Xenopus skin forms anion-permeable channels in planar lipid bilayers. Biophys J. 1989 Nov;56(5):1017-21.
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