RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.

Methylene Violet 3RAX, a phenazine dye, is utilized for staining cell mitochondria and has the capability to alter DNA's molecular structure, disrupt DNA modules, and promote reactive singlet oxygen generation.

5, 7-Dihydroxychromone isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels.