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Cyclo(RGDyK)
CAS No. 217099-14-4
Cyclo(RGDyK)( —— )
Catalog No. M30392 CAS No. 217099-14-4
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 200MG | Get Quote | Get Quote |
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Biological Information
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Product NameCyclo(RGDyK)
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NoteResearch use only, not for human use.
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Brief DescriptionCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
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DescriptionCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.(In Vitro):Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).
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In VitroCyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5(IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIC50: 20 nM (αVβ3 Integrin), 3000 nM (αIIbβ3 Integrin), 4000 nM (αVβ5 Integrin)
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Research Area——
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Indication——
Chemical Information
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CAS Number217099-14-4
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Formula Weight619.67
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Molecular FormulaC27H41N9O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 5 mg/mL (8.07 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.
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Cyclo(RGDyK)
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