Cart
sales@molnova.com
Cyclo(RGDyK)
CAS No. 217099-14-4
Cyclo(RGDyK)( —— )
Catalog No. M30392 CAS No. 217099-14-4
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameCyclo(RGDyK)
-
NoteResearch use only, not for human use.
-
Brief DescriptionCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
-
DescriptionCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.(In Vitro):Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).
-
In VitroCyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5(IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetIntegrin
-
RecptorIC50: 20 nM (αVβ3 Integrin), 3000 nM (αIIbβ3 Integrin), 4000 nM (αVβ5 Integrin)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number217099-14-4
-
Formula Weight619.67
-
Molecular FormulaC27H41N9O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 5 mg/mL (8.07 mM)
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.
molnova catalog
related products
-
CASIN
CASIN is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
-
GSK-3008348 hydrochl...
GSK-3008348 hydrochloride is a novel potent, selective integrin αvβ6 antagonist for the treatment of idiopathic pulmonary fibrosis (IPF).
-
LXW7
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-peptide (cGRGDdvc) containing unnatural amino acids flanking both sides of the main functional motif.
