Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - Opioid Receptor - DAMGO (TFA)

DAMGO (TFA)

CAS No. 950492-85-0

DAMGO (TFA)( —— )

Catalog No. M30306 CAS No. 950492-85-0

DAMGO is a selective peptide agonist of the μ-opioid receptor .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 65 Get Quote
10MG 117 Get Quote
25MG 251 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    DAMGO (TFA)
  • Note
    Research use only, not for human use.
  • Brief Description
    DAMGO is a selective peptide agonist of the μ-opioid receptor .
  • Description
    DAMGO is a selective peptide agonist of the μ-opioid receptor .
  • In Vitro
    DAMGO (1-10 μM) TFA significantly reduces the activation of neuronal Akt and ERK1/2 by CXCL12 and inhibits CXCL12-promoted neuronal survival, but does not down-regulate CXCR4 protein expression.DAMGO (1 μM) TFA effectively inhibits the prostaglandin E 2 (PGE 2) induced increase in a tetrodotoxin-resistant voltage-gated Na+ current (TTX-R I Na), i.e. PGE 2 (1 μM) can increase the TTX-R I Na peak by 103 % compared to 24.9 % with the addition of DAMGO.
  • In Vivo
    DAMGO (i.v., 0.5-2 mg/kg) TFA can produce significant anti-injury effects on injured paws of male Sprague-Dawley rats weighing 200-225 g in a dose-dependent manner, producing an effective and long-lasting analgesic effect.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Opioid Receptor
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    950492-85-0
  • Formula Weight
    627.61
  • Molecular Formula
    C28H36F3N5O8
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 125 mg/mL (199.17 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name
    Sequence:Tyr-{d-Ala}-Gly-{Me-Phe}-Gly-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

FEBS Lett. 1995 Jan 2;357(1):93-7. Onogi T, et al. DAMGO, a mu-opioid receptor selective agonist, distinguishes between mu- and delta-opioid receptors around their first extracellular loops.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Apitegromab

    Apitegromab (SRK-015) is a new myostatin inhibitor, an antibody targeting myostatin precursor, which can be used to study neuromuscular diseases including spinal muscular atrophy.

  • Hemorphin-7

    Hemorphin-7 binds to the angiotensin IV receptor, triggering multiple effects including cellular proliferation and memory enhancement. Hemorphins are endogenous peptides belonging to the family of atypical opioid peptides released from hydrolyzed hemoglobin. Hemorphin-7 is investigated as a potential biomarker for breast cancer.

  • Eluxadoline

    A potent, selective, orally bioavailable μ-opioid receptor agonist and a δ-opioid receptor antagonist for the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D).

Sign In Join Free