β-Amyloid 1-17
CAS No. 186319-72-2
β-Amyloid 1-17( —— )
Catalog No. M30199 CAS No. 186319-72-2
This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Nameβ-Amyloid 1-17
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NoteResearch use only, not for human use.
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Brief DescriptionThis synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
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DescriptionThis synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
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In Vitroβ-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).Solid Aβ peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure.The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 ℃. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing.Next, the solution was age 48h at 4-8 ℃. The sample was then centrifuged at 14000g for 10 min at 4-8 ℃; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments.
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number186319-72-2
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Formula Weight2068.2
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Molecular FormulaC90H130N28O29
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}{Leu}
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Shi JM, et al. Dissecting the behaviour of β-amyloid peptide variants during oligomerization and fibrillation. Pept Sci. 2017 Nov;23(11):810-817.
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