PD-1/PD-L1-IN 3 TFA
CAS No. ——
PD-1/PD-L1-IN 3 TFA ( —— )
Catalog No. M30162 CAS No. ——
PD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NamePD-1/PD-L1-IN 3 TFA
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NoteResearch use only, not for human use.
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Brief DescriptionPD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.
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DescriptionPD-1/PD-L1-IN 3 TFA inhibits the binding of human PD-1 to PD-Ll with an IC50 of 9 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorIC50: 9 nM (PD-1/PD-L1)
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight1966.19
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Molecular FormulaC91H127F3N24O20S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:{Maa}{Phe}{Ala}{Asn}{Pro}{His}{Leu}{Sar}{Trp}{Ser}{Trp}{Nle}{Nle}{Arg}{Cys}{Gly} (Disulfide bridge: Maa1-Cys15)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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BC-1471
STAMBP-IN-1 is a small-molecule inhibitor of STAMBP deubiquitinase, and interrupts STAMBP-Ub-NALP7 interaction. STAMBP-IN-1 decreases protein level of its inflammasome substrate NALP7 and suppresses IL-1b release after Toll-like receptor (TLR) agonism. STAMBP-IN-1 inhibits the activity of STAMBP to cleave recombinant di-Ub with an IC50 value of 0.33 mM
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MRK-740
MRK-740 is a potent and selective inhibitor of PRDM9 histone methyltransferase.MRK-740 inhibits other histone methyltransferases and inhibits PRDM9-dependent H3K4 trimethylation.
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Digoxigenin
Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases
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