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GLP-1(7-37) acetate(106612-94-6 free base)

CAS No. 1450806-98-0

GLP-1(7-37) acetate(106612-94-6 free base) ( —— )

Catalog No. M30075 CAS No. 1450806-98-0

Glp-1 (7-37)acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    GLP-1(7-37) acetate(106612-94-6 free base)
  • Note
    Research use only, not for human use.
  • Brief Description
    Glp-1 (7-37)acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
  • Description
    Glp-1 (7-37)acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.(In Vivo):GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats. Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1450806-98-0
  • Formula Weight
    3415.72
  • Molecular Formula
    C153H232N40O49
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 50 mg/mL (14.64 mM)
  • SMILES
    ——
  • Chemical Name
    Sequence:His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Sarrauste de Menthiere, C. et al. Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP production. European journal of medicinal chemistry 39, 473-480, doi:10.1016/j.ejmech.2004.02.002 (2004).
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