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β-Amyloid (1-42), rat TFA
CAS No. ——
β-Amyloid (1-42), rat TFA( —— )
Catalog No. M30036 CAS No. ——
β-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Nameβ-Amyloid (1-42), rat TFA
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NoteResearch use only, not for human use.
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Brief Descriptionβ-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease.
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Descriptionβ-Amyloid (1-42), rat TFA is a 42-aa peptide, shows the effects of cytotoxicity on acute hippocampal slices, and has been used in studies of alzheimer's disease.(In Vitro):β-Amyloid (1-42), rat shows cytotoxic effect on the hippocampal slices at 20 μM. β-Amyloid (1-42), rat causes morphological changes in NGF-induced PC12 cells, induces formed cell processes to retract in differentiated cells and affect the expression of exons 2/3 in both undifferentiated and differentiated cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAmyloid-β
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight4532.04
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Molecular FormulaC199H307N53O59S.C2HF3O2
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL (22.07 mM; Need ultrasonic);H2O : < 0.1 mg/mL (insoluble)
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SMILES——
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Chemical NameSequence:Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Mozes E, et al. A novel method for the rapid determination of beta-amyloid toxicity on acute hippocampal slices using MTT and LDH assays. Brain Res Bull. 2012 Apr 10;87(6):521-5.
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