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M2N12
CAS No. 2376577-06-7
M2N12 ( —— )
Catalog No. M26288 CAS No. 2376577-06-7
M2N12 is a potent and highly selective inhibitor of cell division cycle 25C protein phosphatase (Cdc25C, IC50 = 0.09 μM). M2N12 has anti-tumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 222 | Get Quote |
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| 10MG | 357 | Get Quote |
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| 25MG | 597 | Get Quote |
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| 50MG | 851 | Get Quote |
|
| 100MG | 1152 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameM2N12
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NoteResearch use only, not for human use.
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Brief DescriptionM2N12 is a potent and highly selective inhibitor of cell division cycle 25C protein phosphatase (Cdc25C, IC50 = 0.09 μM). M2N12 has anti-tumor activity.
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DescriptionM2N12 is a potent and highly selective inhibitor of cell division cycle 25C protein phosphatase (Cdc25C, IC50 = 0.09 μM). M2N12 has anti-tumor activity. M2N12 also has promising activity against Cdc25A(IC50 = 0.53? μM) and Cdc25B(IC50 = 1.39 μM).(In Vitro):M2N12 has cytotoxic activity against five tumor cell lines and a normal cell line including A-549(IC50 = 3.92 μM), MDA-MB-231(IC50 = 4.63 μM), KB(IC50 = 5.05 μM), KB-VIN(IC50 = 6.81 μM), MCF-7(IC50 = 4.71 μM) and HBE(IC50 = 6.00 μM).
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2376577-06-7
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Formula Weight393.8
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Molecular FormulaC20H16ClN5O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1ccc(Cn2cc(CNC3=C(Cl)C(=O)c4cccnc4C3=O)nn2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Davies FK, Work VH, Beliaev AS, Posewitz MC. Engineering Limonene and Bisabolene Production in Wild Type and a Glycogen-Deficient Mutant of Synechococcus sp. PCC 7002. Front Bioeng Biotechnol. 2014 Jun 19;2:21.
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