Jagged-1 (188-204) TFA( —— )

Catalog No. M29992 CAS No. ——

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Jagged-1 (188-204) TFA
Note

Research use only, not for human use.
Brief Description

Jagged-1 (188-204) TFA is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-alphaB activation.
Description

Jagged-1 (188-204) TFA is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-alphaB activation.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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CAS Number

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Formula Weight

2221.42
Molecular Formula

C95H128F3N25O28S3
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

Sequence:{Cys}{Asp}{Asp}{Tyr}{Tyr}{Tyr}{Gly}{Phe}{Gly}{Cys}{Asn}{Lys}{Phe}{Cys}{Arg}{Pro}{Arg}