Fz7-21 TFA (2247635-23-8 free base)( (Ac)-LPSDDLEFWCHVMY-NH2 TFA )

Catalog No. M29961 CAS No. ——

Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Fz7-21 TFA (2247635-23-8 free base)
Note

Research use only, not for human use.
Brief Description

Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.
Description

Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.
In Vitro

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In Vivo

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Synonyms

(Ac)-LPSDDLEFWCHVMY-NH2 TFA
Pathway

Others
Target

Other Targets
Recptor

EC50: 58 nM (human FZD7 CRD), 34 nM (mouse FZD7 CRD)
Research Area

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Indication

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Chemical Information

CAS Number

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Formula Weight

1910.07
Molecular Formula

C85H115N18F3O25S2
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

Sequence:(Ac)-{Leu}{Pro}{Ser}{Asp}{Asp}{Leu}{Glu}{Phe}{Trp}{Cys}{His}{Val}{Met}{Tyr}-NH2

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Nile AH, et al. Publisher Correction: A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat Chem Biol. 2018 Sep;14(9):902.

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