Totarol

Research use only, not for human use.

Totarol shows antibacterial effects against several pathogenic Gram-positive bacteria, mycobacterium tuberculosis.

Totarol shows antibacterial effects against several pathogenic Gram-positive bacteria, mycobacterium tuberculosis.(In Vitro):Totarol (2 μM) inhibits the proliferation of Bacillus subtilis cells and strongly induces the filamentation in B. subtilis cells. Totarol (1.5 μM) reduces the frequency of the Z-ring occurrence per micrometer of the bacterial cell length but did not affect the nucleoid frequency, suggesting that it blocks cytokinesis by inhibiting the formation of the Z-ring. Totarol perturbs the assembly dynamics of FtsZ protofilaments in the Z-ring.

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(+)-Totarol

GPCR/G Protein

Antibacterial

Antibacterial

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511-15-9

286.459

C20H30O

>98% (HPLC)

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CC(C)c1c(O)ccc2c1CC[C@H]1C(C)(C)CCC[C@]21C

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(-20℃)

With Ice Pack

≥ 2 years