Garcinone C

Research use only, not for human use.

Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.

Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.(In Vitro):Garcinone C is active against both of pathogenic (MIC =100 μg/ml) and non-pathogenic leptospira (MIC = 200 μg/ml). Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3, and CDK7. Garcinone C significantly inhibits cell viability of the human nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1, and HONE1 in a time and dose dependent manner.

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Cell Cycle/DNA Damage

AChR

AChR

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76996-27-5

414.454

C23H26O7

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (241.28 mM)

CC(C)=CCc1c(O)cc2oc3cc(O)c(O)c(CCC(C)(C)O)c3c(=O)c2c1O

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(-20℃)

With Ice Pack

≥ 2 years