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3,4-O-Isopropylidene-shikimic acid
CAS No. 183075-03-8
3,4-O-Isopropylidene-shikimic acid( 3,4-O-Isopropylidene shikimic acid | 3,4-O-Isopropylidene-shikimic acid )
Catalog No. M29070 CAS No. 183075-03-8
3,4-Oxo- isopropylidene-shikimic acid has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 164 | In Stock |
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| 5MG | 160 | In Stock |
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| 10MG | 236 | In Stock |
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| 25MG | 392 | In Stock |
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| 50MG | 549 | In Stock |
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| 100MG | 742 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name3,4-O-Isopropylidene-shikimic acid
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NoteResearch use only, not for human use.
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Brief Description3,4-Oxo- isopropylidene-shikimic acid has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.
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Description3,4-Oxo- isopropylidene-shikimic acid has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.(In Vitro):3,4-O-Isopropylidene shikimic acid (ISA,1-100 micromol/L) effectively reduced PMN adhesion to TNF-alpha-induced HUVEC with the inhibitory rate from 17.2 % to 53.5 % and exerted no effect on PMN adhesion to normal HUVEC. Adhesion molecule ICAM-1 surface protein and mRNA expression induced by TNF-alpha (400 kU/L) were significantly inhibited by ISA. In addition, the cell viability of HUVEC was unchanged 48 h after treatment with ISA.
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In Vitro——
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In Vivo——
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Synonyms3,4-O-Isopropylidene shikimic acid | 3,4-O-Isopropylidene-shikimic acid
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PathwayImmunology/Inflammation
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TargetNOS
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RecptorNOS
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Research Area——
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Indication——
Chemical Information
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CAS Number183075-03-8
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Formula Weight214.2
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Molecular FormulaC10H14O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (466.81 mM)
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SMILESCC(C)(O[C@H]1[C@@H](C2)O)O[C@@H]1C=C2C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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AVE-9488
AVE-9488 is a novel endothelial NO synthase (eNOS) enhancer that upregulates eNOS expression, induces NO production, and may ameliorate portal hypertension.
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TP508
TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibroblasts.TP508 (Chrysalin) is an investigational peptide drug that was developed for use in stimulating repair of dermal and musculoskeletal tissues.
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S-Nitroso-N-acetyl-D...
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