(2S)-2'-Methoxykurarinone
CAS No. 270249-38-2
(2S)-2'-Methoxykurarinone( 2'-Methoxykurarinone | 2'-O-Methylkurarinone )
Catalog No. M29067 CAS No. 270249-38-2
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name(2S)-2'-Methoxykurarinone
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NoteResearch use only, not for human use.
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Brief Description(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects.
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Description(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells.(In Vitro):2'-Methoxykurarinone has strong alpha-glucosidase inhibitory activities, with IC(50) values of 155 microM. 2'-Methoxykurarinone is a noncompetitive inhibitor of protein tyrosine phosphatase 1B.
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In Vitro——
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In Vivo——
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Synonyms2'-Methoxykurarinone | 2'-O-Methylkurarinone
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorAkt
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Research Area——
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Indication——
Chemical Information
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CAS Number270249-38-2
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Formula Weight452.547
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Molecular FormulaC27H32O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (55.24 mM)
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SMILESCOc1cc(O)ccc1[C@@H]1CC(=O)c2c(OC)cc(O)c(C[C@@H](CC=C(C)C)C(C)=C)c2O1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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