Gomisin D

Research use only, not for human use.

Gomisin D is a natural product.Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule.Gomisin D is a potential antidiabetic and anti-Alzheimer’s agent.

Gomisin D is a natural product.Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule.Gomisin D is a potential antidiabetic and anti-Alzheimer’s agent.(In Vitro):Using exhaustive chromatographic separation we have isolated (-)-tigloyl-deangeloyl-gomisin F as a novel dibenzocyclooctadiene lignan from schisandra chinensis. With the help of HPLC, we further isolated (+)-schisandrin, (+)-deoxyschisandrin, (+)-γ-schisandrin, (-)-gomisin J, (+)-gomisin A, (-)-gomisin N, (-)-tigloyl-gomisin P, (-)-wuweizisu C, (-)-Gomisin D, rubrisandrin A, (-)-gomisin G, (+)-gomisin K (3) and (-)-schisantherin C. A full NMR description of (-)-schisantherin C was carried out with the aim to confirm previous reports of its structure. Compounds isolated were identified on the basis of UV, IR, (1)H- and (13)C-NMR and MS. The cytotoxicity of lignans was tested for the BY-2 cell line alone and as a synergistic effect with the cytotoxic agent camptothecin.

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Others

Other Targets

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60546-10-3

530.57

C28H34O10

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (188.48 mM)

COc1cc2C3OC(=O)C(C)(O)C(C)COc4c5OCOc5cc(C[C@H](C)[C@@]3(C)O)c4-c2c(OC)c1OC

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(-20℃)

With Ice Pack

≥ 2 years