Elevenostat( JB3-22 )

Catalog No. M28876 CAS No. 1454902-97-6

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	41	In Stock
5MG	37	In Stock
10MG	61	In Stock
25MG	116	In Stock
50MG	183	In Stock
100MG	341	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Elevenostat
Note

Research use only, not for human use.
Brief Description

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.
Description

Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 μM.(In Vitro):Elevenostat induced cell death in MM cell lines.(In Vivo):Elevenostat produced similar anti-MM activity in vivo, improving survival among mice inoculated with 5TGM1 MM cells.
In Vitro

——
In Vivo

——
Synonyms

JB3-22
Pathway

Cell Cycle/DNA Damage
Target

HDAC
Recptor

Telomerase
Research Area

——
Indication

——

Chemical Information

CAS Number

1454902-97-6
Formula Weight

315.32
Molecular Formula

C16H17N3O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (792.85 mM)
SMILES

COc(cccc1)c1NC(NCc(cc1)ccc1C(NO)=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Fleming AM, et al. Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. 2018 Feb 13;57(6):991-1002.

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