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2'-Fluoro-2'-Deoxyadenosine
2'-Fluoro-2'-Deoxyadenosine
CAS No. 64183-27-3
2'-Fluoro-2'-Deoxyadenosine( —— )
Catalog No. M28866 CAS No. 64183-27-3
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | 27 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name2'-Fluoro-2'-Deoxyadenosine
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NoteResearch use only, not for human use.
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Brief Description2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).
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Description2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors expressing E. coli PNP. 2'-Fluoro-2'-Deoxyadenosine can be used to synthesize 2'-deoxy-2'-fluoromodified oligonucleotides that can hybridize to RNA.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetNucleoside Antimetabolite/Analog
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number64183-27-3
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Formula Weight269.236
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Molecular FormulaC10H12FN5O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (185.71 mM)
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SMILESNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chatterjee A , Sarkar S , Saha S K . Acacetin 7- O-β- d-galactopyranoside from Chrysanthemum indicum[J]. Phytochemistry, 1981, 20(7):1760-1761.
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