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ML328

CAS No. 634175-34-1

ML328( —— )

Catalog No. M28826 CAS No. 634175-34-1

ML328 is a potent and selective inhibitor of bacterial AddAB(IC50 = 1.0 μM) and RecBCD(IC50 = 4.8 μM) helicase-nucleases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 157 In Stock
5MG 140 In Stock
10MG 227 In Stock
25MG 432 In Stock
50MG 618 In Stock
100MG 863 In Stock
200MG 1172 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    ML328
  • Note
    Research use only, not for human use.
  • Brief Description
    ML328 is a potent and selective inhibitor of bacterial AddAB(IC50 = 1.0 μM) and RecBCD(IC50 = 4.8 μM) helicase-nucleases.
  • Description
    ML328 is a potent and selective inhibitor of bacterial AddAB(IC50 = 1.0 μM) and RecBCD(IC50 = 4.8 μM) helicase-nucleases.(In Vitro):The probe ML328 has a half-life of over 48 hours in PBS at room temperature when tested at 10 μM. Disappearance of the LC peak for the probe is unaltered by the addition of excess glutathione (50 μM) in a 6 hour incubation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Bcl-2|Caspase-3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    634175-34-1
  • Formula Weight
    506.5
  • Molecular Formula
    C22H21F3N6O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (49.36 mM)
  • SMILES
    CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)Nc1cccc(c1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yao H, et al. Thevetiaflavone from Wikstroemia indica ameliorates PC12 cells injury induced by OGD/R via improving ROS?mediated mitochondrial dysfunction. Mol Med Rep. 2017 Dec;16(6):9197-9202.
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