GRL-0496

CAS No. 1087243-14-8

GRL-0496( —— )

Catalog No. M28825 CAS No. 1087243-14-8

GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 64 In Stock
2MG 36 In Stock
5MG 57 In Stock
10MG 93 In Stock
25MG 198 In Stock
50MG 334 In Stock
100MG 569 In Stock
200MG Get Quote In Stock
500MG 1190 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GRL-0496
  • Note
    Research use only, not for human use.
  • Brief Description
    GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μM.
  • Description
    GRL-0496 is a potent inhibitor with an enzyme inhibitory activity against SARS-CoV 3CLpro with an IC50 of 30 nM and antiviral potency with an EC50 value of 6.9 μM.
  • In Vitro
    GRL-0496 shows the best SARS-CoV antiviral activity, with an EC EC50 of 6.9 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Topo I|DPPH|Antioxidant
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1087243-14-8
  • Formula Weight
    272.69
  • Molecular Formula
    C14H9ClN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (366.72 mM)
  • SMILES
    O=C(c1c(cc[nH]2)c2ccc1)Oc1cc(Cl)cnc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Preparative isolation of six anti-tumour biflavonoids from Selaginella doederleinii Hieron by high-speed counter-current chromatography.Phytochem Anal. 2014 Mar-Apr;25(2):127-33.
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