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Cedirogant
CAS No. 2055496-11-0
Cedirogant( ABBV-157 )
Catalog No. M28818 CAS No. 2055496-11-0
Cedirogant is an orally active retinoid-related orphan receptor-γt(RORγt) inverse agonist that is used for psoriasis study.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 245 | Get Quote |
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| 10MG | 390 | Get Quote |
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| 25MG | 650 | Get Quote |
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| 50MG | 888 | Get Quote |
|
| 100MG | 1242 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCedirogant
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NoteResearch use only, not for human use.
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Brief DescriptionCedirogant is an orally active retinoid-related orphan receptor-γt(RORγt) inverse agonist that is used for psoriasis study.
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DescriptionCedirogant is an orally active retinoid-related orphan receptor-γt(RORγt) inverse agonist that is used for psoriasis study.
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In VitroThe transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17 cell differentiation and IL-17/22 production and is therefore an attractive target for the treatment of inflammatory diseases. Cedirogant (ABBV-157) has the potential for chronic plaque psoriasis research.
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In Vivo——
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SynonymsABBV-157
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PathwayNuclear Receptor/Transcription Factor
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TargetROR
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2055496-11-0
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Formula Weight547.78
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Molecular FormulaC24H20Cl3F3N2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (456.39 mM)
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SMILESOC(CC(CC1)CCN1C(c(ccc(Cl)c1Cn(ccc2cc(C(F)(F)F)c3)c2c3Cl)c1Cl)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wu Y, et al. Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. J Biomol Screen. 2016 Jan;21(1):74-87.
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