Cart
sales@molnova.com
Home - Products - Others - Other Targets - (S,R,S)-AHPC-Me

(S,R,S)-AHPC-Me

CAS No. 1948273-02-6

(S,R,S)-AHPC-Me( VHL ligand 2 | E3 ligase Ligand 1A )

Catalog No. M28565 CAS No. 1948273-02-6

(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me can be used to synthesize ARV-771.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 29 In Stock
50MG 45 In Stock
100MG 60 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    (S,R,S)-AHPC-Me
  • Note
    Research use only, not for human use.
  • Brief Description
    (S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me can be used to synthesize ARV-771.
  • Description
    (S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VHL ligand 2 | E3 ligase Ligand 1A
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    α1A-adrenergic receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1948273-02-6
  • Formula Weight
    444.59
  • Molecular Formula
    C23H32N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (562.32 mM)
  • SMILES
    C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](N)C(C)(C)C)c1ccc(cc1)-c1scnc1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Williams TJ, et al. In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists. Br J Pharmacol. 1999 May;127(1):252-8.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Fz7-21 TFA (2247635-...

    Fz7-21 TFA ((Ac)-LPSDDLEFWCHVMY-NH2 TFA), a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively.

  • moxaprindine

    Moxaprindine is an alprindine derivative with antiarrhythmic activity.

  • alanine

    Alanine is an Amino Acid. The chemical classification of alanine is Amino Acids. Alanine is a small non-essential amino acid in humans.

Sign In Join Free