Cart
sales@molnova.com
BV02
CAS No. 292870-53-2
BV02( 2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid )
Catalog No. M28532 CAS No. 292870-53-2
BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 53 | In Stock |
|
| 2MG | 29 | In Stock |
|
| 5MG | 48 | In Stock |
|
| 10MG | 73 | In Stock |
|
| 25MG | 164 | In Stock |
|
| 50MG | 254 | In Stock |
|
| 100MG | 375 | In Stock |
|
| 200MG | 533 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBV02
-
NoteResearch use only, not for human use.
-
Brief DescriptionBV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.
-
DescriptionBV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.
-
In Vitro——
-
In Vivo——
-
Synonyms2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxoisoindoline-5-carboxylic acid
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number292870-53-2
-
Formula Weight377.35
-
Molecular FormulaC20H15N3O5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 12.5 mg/mL (33.13 mM)
-
SMILESO=C(O)C1=CC=C2C(=O)N(C(=O)C2=C1)C=3C(=O)N(C=4C=CC=CC4)N(C3C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
H-Gly-Gly-Pro-OH
H-Gly-Pro-OH is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism that is further cleaved by prolidase.
-
[Ala286]-Calmodulin-...
[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors.
-
ACT-389949
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes.
