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Bisdionin C
CAS No. 74857-22-0
Bisdionin C( —— )
Catalog No. M28336 CAS No. 74857-22-0
Bisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 = 3.4 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 124 | In Stock |
|
| 25MG | 226 | In Stock |
|
| 50MG | 333 | In Stock |
|
| 100MG | 485 | In Stock |
|
| 200MG | 668 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBisdionin C
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NoteResearch use only, not for human use.
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Brief DescriptionBisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 = 3.4 μM).
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DescriptionBisdionin C is a potent inhibitor of GH18 chitinase with an IC50 of 0.2 μM for A. fumigatus ChiB1. Bisdionin C inhibits human macrophage chitotriosidase(HCHT, IC50 = 8.3 μM) and acidic mammalian chitinase (AMCase, IC50 = 3.4 μM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorCCR5|hERG|P-gp
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Research Area——
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Indication——
Chemical Information
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CAS Number74857-22-0
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Formula Weight400.399
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Molecular FormulaC17H20N8O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 2 mg/mL (5.00 mMultr)
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SMILESCn1cnc2n(C)c(=O)n(CCCn3c(=O)n(C)c4ncn(C)c4c3=O)c(=O)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Elsby R, et al. The utility of in vitro data in making accurate predictions of human P-glycoprotein-mediated drug-drug interactions: a case study for AZD5672. Drug Metab Dispos. 2011 Feb;39(2):275-82.
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