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Thalidomide-5-methyl
CAS No. 40313-92-6
Thalidomide-5-methyl( —— )
Catalog No. M28307 CAS No. 40313-92-6
Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 132 | In Stock |
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| 5MG | 147 | In Stock |
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| 10MG | 221 | In Stock |
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| 25MG | 378 | In Stock |
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| 50MG | 520 | In Stock |
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| 100MG | 703 | In Stock |
|
| 200MG | 949 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameThalidomide-5-methyl
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
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DescriptionThalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorhDHODH
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Research Area——
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Indication——
Chemical Information
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CAS Number40313-92-6
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Formula Weight272.26
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Molecular FormulaC14H12N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCc(cc1)cc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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RBC10
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines.
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24-Dihydroxypyrimidi...
24-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.
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Remimazolam
Remimazolam is a benzodiazepine derivative drug as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures.?Remimazolam was found to be both faster acting and shorter lasting than midazolam, and human clinical trials showed a faster recovery time and predictable, consistent pharmacokinetics, suggesting some advantages over existing drugs for these applications.?
