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Home - Products - Others - Other Targets - Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

CAS No. 2225940-47-4

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-( 4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid )

Catalog No. M28268 CAS No. 2225940-47-4

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
  • Note
    Research use only, not for human use.
  • Brief Description
    Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.
  • Description
    Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.(In Vitro):Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino] s a functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC3 linker with terminal acid ready for conjugation to a target protein ligand.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    TRPC6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2225940-47-4
  • Formula Weight
    359.33
  • Molecular Formula
    C17H17N3O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)CCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.H?fner S, Urban N, Schaefer M. Discovery and characterization of a positive allosteric modulator of transient receptor potential canonical 6 (TRPC6) channels. Cell Calcium. 2019 Mar;78:26-34.
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