Cart
sales@molnova.com
ARV-471
CAS No. 2229711-68-4
ARV-471( —— )
Catalog No. M28234 CAS No. 2229711-68-4
ARV-471 is a best-in-class, orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 851 | In Stock |
|
| 5MG | 437 | In Stock |
|
| 10MG | 622 | In Stock |
|
| 25MG | 924 | In Stock |
|
| 50MG | 1230 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameARV-471
-
NoteResearch use only, not for human use.
-
Brief DescriptionARV-471 is a best-in-class, orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
-
DescriptionARV-471 is a best-in-class, orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetEstrogen Receptor/ERR
-
RecptornAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2229711-68-4
-
Formula Weight723.9
-
Molecular FormulaC45H49N5O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 110 mg/mL (151.95 mM)
-
SMILESOc1cc(CC[C@@H]([C@@H]2c(cc3)ccc3N3CCC(CN(CC4)CCN4c(cc4)cc(CN5[C@@H](CCC(N6)=O)C6=O)c4C5=O)CC3)c3ccccc3)c2cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Matthew J. Cheesman . Oceania: Antidepressant Medicinal Plants. Herbal Medicine in Depression. 2016, 483-527.
molnova catalog
related products
-
17-Beta-Estradiol-3,...
Estradiol dipropionate is a synthetic ester, specifically the 3,17-dipropanoyl ester, of the natural estrogen, estradiol.
-
PHTPP
A potent, selective antagonist of estrogen ERβ receptor; exhibits 36-fold selective for ERβ, and is fully effective as an ERα antagonist.
-
Acolbifene
Acolbifene is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.
