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4-CPPC

CAS No. 29553-70-6

4-CPPC( —— )

Catalog No. M28169 CAS No. 29553-70-6

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	126	In Stock
5MG	116	In Stock
10MG	188	In Stock
25MG	432	In Stock
50MG	625	In Stock
100MG	889	In Stock
200MG	Get Quote	In Stock
500MG	1786	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

4-CPPC
Note

Research use only, not for human use.
Brief Description

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).
Description

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PXR
Research Area

——
Indication

——

Chemical Information

CAS Number

29553-70-6
Formula Weight

287.227
Molecular Formula

C14H9NO6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (348.17 mM)
SMILES

OC(=O)c1cccc(c1)-c1cc(ncc1C(O)=O)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lin W, et, al. SPA70 is a potent antagonist of human pregnane X receptor. Nat Commun. 2017 Sep 29;8(1):741.

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