Cart
sales@molnova.com
Home -
Products -
Cell Cycle/DNA Damage -
Nucleoside Antimetabolite/Analog -
2′-Deoxy-2′-fluoroguanosine
2′-Deoxy-2′-fluoroguanosine
CAS No. 78842-13-4
2′-Deoxy-2′-fluoroguanosine( —— )
Catalog No. M28163 CAS No. 78842-13-4
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 32 | In Stock |
|
| 500MG | 49 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name2′-Deoxy-2′-fluoroguanosine
-
NoteResearch use only, not for human use.
-
Brief Description2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.
-
Description2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetNucleoside Antimetabolite/Analog
-
RecptorDYRK1A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number78842-13-4
-
Formula Weight285.235
-
Molecular FormulaC10H12FN5O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (175.30 mM)
-
SMILESNc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Liu YA, et al. Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133. J Med Chem. 2020 Mar 26;63(6):2958-2973.
molnova catalog
related products
-
TAS-114
TAS-114 is a first-in-class, potent, dual dUTPase/DPD inhibitor with Ki of 0.13/2.14 uM, respectively.
-
Metesind glucuronate
Metesind glucuronate (AG 331;AG-265 glucuronate) is a potent thymidylate synthase (TS) inhibitor with IC50/IC90 of 0.7/3.0 uM.
-
DMT-2′Fluoro-dU Phos...
DMT-2′Fluoro-dU Phosphoramidite can be used to modify nucleosides.
