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2′-Deoxy-2′-fluoroguanosine
2′-Deoxy-2′-fluoroguanosine
CAS No. 78842-13-4
2′-Deoxy-2′-fluoroguanosine( —— )
Catalog No. M28163 CAS No. 78842-13-4
2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 32 | In Stock |
|
| 500MG | 49 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name2′-Deoxy-2′-fluoroguanosine
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NoteResearch use only, not for human use.
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Brief Description2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.
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Description2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetNucleoside Antimetabolite/Analog
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RecptorDYRK1A
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Research Area——
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Indication——
Chemical Information
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CAS Number78842-13-4
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Formula Weight285.235
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Molecular FormulaC10H12FN5O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (175.30 mM)
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SMILESNc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu YA, et al. Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133. J Med Chem. 2020 Mar 26;63(6):2958-2973.
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