Cart
sales@molnova.com
CAY10781
CAS No. 1210360-87-4
CAY10781( —— )
Catalog No. M28128 CAS No. 1210360-87-4
CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 72 | In Stock |
|
| 2MG | 33 | In Stock |
|
| 5MG | 49 | In Stock |
|
| 10MG | 70 | In Stock |
|
| 25MG | 126 | In Stock |
|
| 50MG | 177 | In Stock |
|
| 100MG | 327 | In Stock |
|
| 200MG | 458 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCAY10781
-
NoteResearch use only, not for human use.
-
Brief DescriptionCAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
-
DescriptionCAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptorneutral sphingomyelinase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1210360-87-4
-
Formula Weight231.211
-
Molecular FormulaC11H9N3O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOC(=O)Cc1cnc([nH]c1=O)-c1cccnc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.
molnova catalog
related products
-
Hemiphroside A
Hemiphroside A is a natural product from Hydrangea macrophylla.
-
S-(5-Adenosyl)-L-met...
S-(5'-Adenosyl)-L-methionine chloride is a natural product. S-(5'-Adenosyl)-L-methionine chloride can be used as a reference standard.
-
Carpachromene
Carpachromene could be a potential anti-inflammatory agent, it blocks protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-stimulated macrophages.Carpachromene shows significant α-glucosidase inhibitory activity.
