Salinazid
CAS No. 495-84-1
Salinazid( Salizid | Nilazid | Nupasal | Salizide | Salicylaldehyde isonicotinoyl hydrazone | SIH1 | )
Catalog No. M28013 CAS No. 495-84-1
Salinazid is a potent Cu(II) ionophore which preferentially kills HepG2 cells over HUVEC cells, and is superior to clioquinol.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 10MG | 28 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSalinazid
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NoteResearch use only, not for human use.
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Brief DescriptionSalinazid is a potent Cu(II) ionophore which preferentially kills HepG2 cells over HUVEC cells, and is superior to clioquinol.
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DescriptionSalinazid is a potent Cu(II) ionophore which preferentially kills HepG2 cells over HUVEC cells, and is superior to clioquinol.
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In Vitro——
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In Vivo——
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SynonymsSalizid | Nilazid | Nupasal | Salizide | Salicylaldehyde isonicotinoyl hydrazone | SIH1 |
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PathwayOthers
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TargetOther Targets
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RecptorAntifungal|tuberculosis
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Research Area——
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Indication——
Chemical Information
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CAS Number495-84-1
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Formula Weight241.25
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Molecular FormulaC13H11N3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 250 mg/mL (1036.27 m)
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SMILESO=C(N/N=C/C1=CC=CC=C1O)C2=CC=NC=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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FIDAS-5
FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding.?FIDAS-5 has anticancer activities.?FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM.FIDAS-5 induces the expression of cell cycle inhibitor, p21WAF1/CIP1. FIDAS-5 (3 μM; 36 h) treatment reduces the levels of both S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in LS174T cells.FIDAS-5 (3 μM; 7 days; LS174T cells) treatment significantly inhibits the proliferation of LS174T cells.
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