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Rapastinel acetate
CAS No. 491872-39-0
Rapastinel acetate( Rapastinel acetate (117928-94-6 Free base) )
Catalog No. M28008 CAS No. 491872-39-0
Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 393 | Get Quote |
|
| 10MG | 581 | Get Quote |
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| 25MG | 888 | Get Quote |
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| 50MG | 1242 | Get Quote |
|
| 100MG | 1674 | Get Quote |
|
| 500MG | 3348 | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameRapastinel acetate
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NoteResearch use only, not for human use.
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Brief DescriptionRapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.
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DescriptionRapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.(In Vivo):Rapastinel acetate (3mg/kg; i.v.) facilitated long-term potentiation (LTP) 1day-2weeks but not 4weeks post-dosing. Biweekly dosing with Rapastinel acetate sustained this effect for at least 8weeks. A single dose of Rapastinel acetate increased the proportion of whole-cell NMDAR current contributed by NR2B-containing NMDARs in the hippocampus 1week post-dosing, which returned to baseline by 4weeks post-dosing.
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In Vitro——
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In Vivo——
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SynonymsRapastinel acetate (117928-94-6 Free base)
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PathwayMembrane Transporter/Ion Channel
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TargetNMDAR
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RecptorLipid|Mitochondria|iron chelator
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Research Area——
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Indication——
Chemical Information
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CAS Number491872-39-0
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Formula Weight473.52
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Molecular FormulaC20H35N5O8
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Purity>98% (HPLC)
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Solubility——
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SMILESC(C)(O)=O.C(=O)([C@H]1N(C([C@H]([C@@H](C)O)N)=O)CCC1)N2[C@H](C(N[C@@H]([C@@H](C)O)C(N)=O)=O)CCC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Shachar DB, et al. Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats. Neuropharmacology. 2004 Feb;46(2):254-63.
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