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Harman hydrochloride

CAS No. 21655-84-5

Harman hydrochloride( Harmane hydrochloride(486-84-0 Free base) )

Catalog No. M27979 CAS No. 21655-84-5

Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 34 In Stock
25MG 61 In Stock
50MG 91 In Stock
100MG 129 In Stock
200MG 204 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Harman hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
  • Description
    Harman hydrochloride can directly induce CYP1A1 gene expression in an AhR-dependent manner and may represent a novel mechanism by which harman promotes mutagenicity, co-mutagenicity and carcinogenicity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Harmane hydrochloride(486-84-0 Free base)
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    Autophagy
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21655-84-5
  • Formula Weight
    218.68
  • Molecular Formula
    C12H11ClN2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1nccc2c1[nH]c1c2cccc1.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Páchniková G, et al. Substituted 2-hydroxy-N-(arylalkyl)benzamide sensitizes cancer cells to metabolic stress by disrupting actin cytoskeleton and inhibiting autophagic flux. Toxicol In Vitro. 2016 Dec;37:70-78.
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