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21-deacetyldeflazacort
CAS No. 13649-57-5
21-deacetyldeflazacort( —— )
Catalog No. M27940 CAS No. 13649-57-5
21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 77 | In Stock |
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| 5MG | 70 | In Stock |
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| 10MG | 112 | In Stock |
|
| 25MG | 214 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name21-deacetyldeflazacort
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NoteResearch use only, not for human use.
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Brief Description21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.
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Description21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.(In Vitro):21-deacetyldeflazacort displaces [3H]dexamethasone from its cytosol receptor sites in rat kidney, thymus and liver in vitro.(In Vivo):21-deacetyldeflazacort inhibited 48-h homologous passive cutaneous anaphylaxis in rats, but had no significant effects on active systemic anaphylaxis in mice, on the Schultz-Dale reaction in the isolated guinea-pig trachea or on compound 48/80-induced histamine release in rat peritoneal mast cells. 21-deacetyldeflazacort inhibited reversed cutaneous anaphylaxis in rats and the Arthus reaction in mice.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number13649-57-5
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Formula Weight399.487
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Molecular FormulaC23H29NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (625.81 mM)
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SMILESCC1=N[C@@]2([C@@H](C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C)O1)C(=O)CO
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Thielen LA, et al. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. Cell Metab. 2020 Sep 1;32(3):353-365.e8.
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