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(S)-Amisulpride
CAS No. 71675-92-8
(S)-Amisulpride( Esamisulpride | SEP-4199 )
Catalog No. M27838 CAS No. 71675-92-8
(S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a Ki of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 86 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 125 | In Stock |
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| 25MG | 238 | In Stock |
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| 50MG | 369 | In Stock |
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| 100MG | 500 | In Stock |
|
| 200MG | 643 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name(S)-Amisulpride
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NoteResearch use only, not for human use.
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Brief Description(S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a Ki of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.
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Description(S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a Ki of 900 nM. (S)-Amisulpride has antipsychotic and antidepressant effects.
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In Vitro(S)-Amisulpride (Esamisulpride) displays high affinity binding at both D2 and D3 receptors and is approximately twice as potent as racamisulpride and 20–50 times more potent than (R)-amisulpride at these receptors
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In VivoThe (S)-amisulpride (10mg/kg, s.c.) stimulus is rapidly acquired and was shown to be dose-related, time dependent (effective between 30 and 120min) and stereoselective male C57BL/6 mice.
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SynonymsEsamisulpride | SEP-4199
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number71675-92-8
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Formula Weight369.48
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Molecular FormulaC17H27N3O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (270.65 mM)
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SMILESCCN1CCC[C@H]1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.G. Renner, et al. Acute toxicities of pentachlorophenol, pentachloroanisole, tetrachlorohydroquinone, tetrachlorocatechol, tetrachlororesorcinol, tetrachlorodimethoxybenzenes and tetrachlorobenzenediol diacetates administered to mice, Toxicological & Environmental Chemistry, 11:1, 37-50.
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