PSB-1434( PSB 1434 | PSB1434 )

Catalog No. M27788 CAS No. 1619884-65-9

PSB-1434 is a selective and competitive monoamine oxidase B inhibitor with IC50 of 1.59 nM, selectivity versus MAO-A>6000-fold.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

PSB-1434
Note

Research use only, not for human use.
Brief Description

PSB-1434 is a selective and competitive monoamine oxidase B inhibitor with IC50 of 1.59 nM, selectivity versus MAO-A>6000-fold.
Description

PSB-1434 is a selective and competitive monoamine oxidase B inhibitor with IC50 of 1.59 nM, selectivity versus MAO-A>6000-fold.
In Vitro

——
In Vivo

——
Synonyms

PSB 1434 | PSB1434
Pathway

Metabolic Enzyme/Protease
Target

MAO
Recptor

P-gp
Research Area

——
Indication

——

Chemical Information

CAS Number

1619884-65-9
Formula Weight

273.243
Molecular Formula

C14H9F2N3O
Purity

>98% (HPLC)
Solubility

——
SMILES

Fc1ccc(NC(=O)c2ccc3[nH]ncc3c2)cc1F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Qiu Q, et al. Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance. J Med Chem. 2017 Apr 27;60(8):3289-3302.

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