PQ-10

Research use only, not for human use.

PQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.

PQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.(In Vivo):In mice, PQ-10 shows a region-specific increase in 2-DG uptake in the globus pallidus (equivalent to the outer part of the primate pallidus) and lateral habenula .

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PQ-10 shows region-specific increases in 2-DG uptake in the globus pallidus (equivalent to the external segment of the globus pallidus in primates) and the lateral habenula in mice. Animal Model:24 –28 g male C57BL/6 mice, PDE10A WT and KO mice.Dosage:0.16, 0.63, 2.5, and 10 mg/kg Administration:s.c.Result:Showed region-specific increases in 2-DG uptake in the globus pallidus (equivalent to the external segment of the globus pallidus in primates) and the lateral habenula in mice.

PQ 10 | PQ10 | A844337 | A-844337 | A 844337

Angiogenesis

PDE

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927691-21-2

403.442

C22H21N5O3

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (61.97 mM)

COc1cc2ncnc(N3CCC(C3)Oc3cnc4ccccc4n3)c2cc1OC

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(-20℃)

With Ice Pack

≥ 2 years