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PQ-10
CAS No. 927691-21-2
PQ-10( PQ 10 | PQ10 | A844337 | A-844337 | A 844337 )
Catalog No. M27785 CAS No. 927691-21-2
PQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 44 | In Stock |
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| 25MG | 98 | In Stock |
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| 50MG | 152 | In Stock |
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| 100MG | 219 | In Stock |
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| 200MG | 319 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePQ-10
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NoteResearch use only, not for human use.
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Brief DescriptionPQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.
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DescriptionPQ-10 is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.(In Vivo):In mice, PQ-10 shows a region-specific increase in 2-DG uptake in the globus pallidus (equivalent to the outer part of the primate pallidus) and lateral habenula .
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In Vitro——
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In VivoPQ-10 shows region-specific increases in 2-DG uptake in the globus pallidus (equivalent to the external segment of the globus pallidus in primates) and the lateral habenula in mice. Animal Model:24 –28 g male C57BL/6 mice, PDE10A WT and KO mice.Dosage:0.16, 0.63, 2.5, and 10 mg/kg Administration:s.c.Result:Showed region-specific increases in 2-DG uptake in the globus pallidus (equivalent to the external segment of the globus pallidus in primates) and the lateral habenula in mice.
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SynonymsPQ 10 | PQ10 | A844337 | A-844337 | A 844337
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PathwayAngiogenesis
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TargetPDE
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number927691-21-2
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Formula Weight403.442
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Molecular FormulaC22H21N5O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (61.97 mM)
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SMILESCOc1cc2ncnc(N3CCC(C3)Oc3cnc4ccccc4n3)c2cc1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144.
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