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CAY10526
CAS No. 938069-71-7
CAY10526( CAY-10526 | CAY 10526 | BTH )
Catalog No. M27762 CAS No. 938069-71-7
CAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 125 | Get Quote |
|
| 10MG | 222 | Get Quote |
|
| 25MG | 484 | Get Quote |
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| 50MG | 700 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCAY10526
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NoteResearch use only, not for human use.
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Brief DescriptionCAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
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DescriptionCAY10526 is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.(In Vitro):CAY10526 dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 1.8 μM without any effect on COX-2 expression.
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In Vitro——
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In Vivo——
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SynonymsCAY-10526 | CAY 10526 | BTH
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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RecptorCDK
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Research Area——
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Indication——
Chemical Information
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CAS Number938069-71-7
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Formula Weight311.15
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Molecular FormulaC12H7BrO3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 66.67 mg/mL (214.27 mM)
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SMILESOC1OC(=O)C(Br)=C1c1cc2ccccc2s1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tadesse S, Zhu G, Mekonnen LB, Lenjisa JL, Yu M, Brown MP, Wang S. A novel series of N-(pyridin-2-yl)-4-(thiazol-5-yl)pyrimidin-2-amines as highly potent CDK4/6 inhibitors. Future Med Chem. 2017 Sep;9(13):1495-1506.
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