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YM-750

CAS No. 138046-43-2

YM-750( YM 750 | YM-750 )

Catalog No. M27744 CAS No. 138046-43-2

YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 53 In Stock
2MG 30 In Stock
5MG 46 In Stock
10MG 79 In Stock
25MG 159 In Stock
50MG 254 In Stock
100MG 366 In Stock
200MG 533 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    YM-750
  • Note
    Research use only, not for human use.
  • Brief Description
    YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
  • Description
    YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
  • In Vitro
    Foam cells accumulated esterified cholesterol (EC) for 24 h in the presence of acLDL without Cu2+, which is suppressed by KY-455 and YM-750.
  • In Vivo
    ——
  • Synonyms
    YM 750 | YM-750
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    138046-43-2
  • Formula Weight
    452.642
  • Molecular Formula
    C31H36N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (220.93 mM)
  • SMILES
    Cc1cc(C)c(NC(=O)N(Cc2ccc-3c(Cc4ccccc-34)c2)C2CCCCCC2)c(C)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.P J Chu, et al. Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. Jpn J Pharmacol. 1995 Dec;69(4):311-5.
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