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YM-750
CAS No. 138046-43-2
YM-750( YM 750 | YM-750 )
Catalog No. M27744 CAS No. 138046-43-2
YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 53 | In Stock |
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| 2MG | 30 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 79 | In Stock |
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| 25MG | 159 | In Stock |
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| 50MG | 254 | In Stock |
|
| 100MG | 366 | In Stock |
|
| 200MG | 533 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameYM-750
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NoteResearch use only, not for human use.
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Brief DescriptionYM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
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DescriptionYM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
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In VitroFoam cells accumulated esterified cholesterol (EC) for 24 h in the presence of acLDL without Cu2+, which is suppressed by KY-455 and YM-750.
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In Vivo——
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SynonymsYM 750 | YM-750
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number138046-43-2
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Formula Weight452.642
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Molecular FormulaC31H36N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (220.93 mM)
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SMILESCc1cc(C)c(NC(=O)N(Cc2ccc-3c(Cc4ccccc-34)c2)C2CCCCCC2)c(C)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.P J Chu, et al. Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. Jpn J Pharmacol. 1995 Dec;69(4):311-5.
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