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U 89843A
CAS No. 157013-32-6
U 89843A( —— )
Catalog No. M27731 CAS No. 157013-32-6
U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
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| 5MG | 52 | In Stock |
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| 10MG | 77 | In Stock |
|
| 25MG | 181 | In Stock |
|
| 50MG | 313 | In Stock |
|
| 100MG | 421 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameU 89843A
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NoteResearch use only, not for human use.
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Brief DescriptionU 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.
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DescriptionU 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.(In Vitro):In the alpha 1 beta 2 gamma 2 subtype of GABAA receptors expressed in human embryonic kidney cells, U 89843A dose-dependently enhanced 5 microM GABA-induced Cl- currents with a maximal enhancement of 362 +/- 91%, a half-maximal concentration of 2 +/- 0.4 microM and a slope factor of 1.1 +/- 0.4. U 89843A also inhibited [35S]t-butylbicyclophosphorothionate binding in rat cerebrocortical membranes with a similar half-maximal inhibitory concentration.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptoracetylcholinesterase
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Research Area——
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Indication——
Chemical Information
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CAS Number157013-32-6
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Formula Weight321.85
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Molecular FormulaC16H24ClN5
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.Cc1cc2c(nc(nc2n1C)N1CCCC1)N1CCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dafforn A, et al. Acetylcholinesterase inhibition by the ketone transition state analog phenoxyacetone and 1-halo-3-phenoxy-2-propanones. Biochem Biophys Res Commun. 1982 Jan 29;104(2):597-602.
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